tert-Butyl 3-formylpyrrolidine-1-carboxylate

tert-Butyl 3-formylpyrrolidine-1-carboxylate - Names and Identifiers

Name	1-Boc-3-pyrrolidinecarbaldehyde
Synonyms	N-Boc-3-formylpyrrolidine 1-Boc-3-formyl-pyrrolidine N-BOC-3-FORMYL PYRROLIDINE 1-BOC-3-FORMYL-PYRROLIDINE -Boc-3-pyrrolidinecarbaldehyde 1-BOC-3-PYRROLIDINECARBALDEHYDE 1-Boc-3-pyrrolidinecarbaldehyde 1-boc-3-pyrrolidineearbaldehyde 1-BOC-PYRROLIDINE-3-CARBOXALDEHYDE TERT-BUTYL 3-FORMYLPYRROLIDINE-1-CARBOXYLATE tert-Butyl 3-formylpyrrolidine-1-carboxylate tert-butyl 3-formylpyrrolidine-1-carboxylate 3-Formyl-pyrrolidine-1-carboxylic acid tert-butyl ester 3-FORMYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	59379-02-1
InChI	InChI=1/C10H17NO3/c1-10(2,3)14-9(13)11-5-4-8(6-11)7-12/h7-8H,4-6H2,1-3H3
InChIKey	DWLADVOODHZCFV-UHFFFAOYSA-N

tert-Butyl 3-formylpyrrolidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C10H17NO3
Molar Mass	199.25
Density	1.148±0.06 g/cm3(Predicted)
Boling Point	276.3±33.0 °C(Predicted)
Flash Point	120.9°C
Solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.00483mmHg at 25°C
Appearance	Oil
Color	Colourless
pKa	-2.44±0.40(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.47
MDL	MFCD03791257

tert-Butyl 3-formylpyrrolidine-1-carboxylate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R51 - Toxic to aquatic organisms R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

tert-Butyl 3-formylpyrrolidine-1-carboxylate - Introduction

It is an organic compound. It has a molecular formula of C11H19NO3 and a molecular weight of 213.27g/mol.

A solid, usually white crystalline or white powder. It exists in solid form at room temperature and is soluble in organic solvents such as chloroform, dimethylformamide and dichloromethane.

It has important applications in organic synthesis. It is an important intermediate for the synthesis of compounds with pharmacological activity. It can be used as a starting material for the synthesis of amine compounds, such as amino acids, peptides and other organic synthesis in a variety of reaction substrates. In addition, it can also be used as a protective group to protect the active hydrogen atoms in amino acids.

The method of preparing a pyrrolidine carboxylic acid includes reacting pyrrolidine carboxylic acid with dimethyl carbonic acid and trihydrogen chloride to produce 1-Boc-3-pyrrolidine carboxylic acid, which is then oxidized to a metal by reacting with an oxidizing agent such as sodium hypochlorite or hydrogen peroxide.

Regarding safety information, is a chemical that needs to be used and handled under appropriate laboratory conditions. It may be irritating to the eyes, skin and respiratory tract. Wear appropriate protective gloves, glasses and a mask when used. Avoid prolonged inhalation or skin contact, avoid ingestion. In case of contact, rinse immediately with plenty of water. During use and storage, care should be taken to avoid ignition and sparks. Please use under safe operation and refer to the relevant safety data sheet to ensure correct and safe use.

Last Update：2024-04-10 22:29:15